Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep857 | Pituitary - Basic | ECE2016

Combined clinical and gene expression profiling in human ACTH-secreting pituitary tumors

Cassarino Maria Francesca , Cassarino Andrea , Terreni Mariarosa , Ambrogio Alberto Giacinto , Gentilini Davide , Losa Marco , Cavagnini Francesco , Giraldi Francesca Pecori

Introduction: We have previously reported on the considerable variability in ACTH-secreting pituitary adenomas in terms of responses to major modulators in vitro (Pecori Giraldi et al J. Neuroendocrinol. 2011). Further studies revealed also differences in gene expression profiles in specimens analyzed by microarray analysis. Aim of this study is to correlate transcriptome expression pattern in archival human ACTH-secreting adenomas with clinical features of patients p...